Understanding Cytopoint: A Breakthrough Treatment for Your Dog’s Allergies

If your dog constantly scratches, licks, or bites at their skin, you know how distressing it can be — for both of you. Chronic itching is often caused by allergic dermatitis, a common condition in dogs triggered by environmental allergens such as pollen, dust mites, or mold. Until recently, treatment options were limited to steroids or oral medications that could cause side effects. Thankfully, veterinary science has introduced a safer, more targeted solution: Cytopoint.

What Is Cytopoint?

Cytopoint (lokivetmab) is an innovative injectable therapy designed to relieve itching caused by allergic or atopic dermatitis in dogs. Unlike traditional medications that broadly suppress the immune system, Cytopoint works by specifically targeting and neutralizing interleukin-31 (IL-31) — a key protein in the dog’s body responsible for triggering the itch signal to the brain.

In simple terms, Cytopoint “turns off” the itch at its source without interfering with the rest of the immune system. This means fewer side effects and a more natural return to comfort for your dog.

How Does Cytopoint Work?

Cytopoint is a biologic therapy, meaning it’s made from natural proteins rather than synthetic chemicals. It mimics your dog’s own immune antibodies, binding to IL-31 to prevent it from stimulating nerve cells that cause itching. Once administered by your veterinarian as a small injection under the skin, Cytopoint begins working within 24 to 48 hours.

Most dogs experience noticeable relief within a few days, and the effects can last 4 to 8 weeks depending on the individual pet. Because every dog’s immune system is different, your veterinarian will help determine the right dosing schedule for ongoing comfort.

Benefits of Cytopoint

Pet owners and veterinarians alike appreciate Cytopoint for its effectiveness, convenience, and safety. Here are some key benefits:

• Fast-acting relief: Many dogs stop itching within one to two days after their injection.

• Long-lasting results: Relief can last a full month or longer with a single dose.

• Non-steroidal: Unlike corticosteroids or certain oral allergy medications, Cytopoint does not suppress the immune system or require daily dosing.

• Minimal side effects: Since it’s biologically targeted, side effects are rare. Clinical studies have shown Cytopoint to be safe for dogs of all ages, breeds, and sizes — even those with other health conditions.

• Improved quality of life: With reduced itching, dogs can finally rest, heal, and enjoy a better quality of life.

What to Expect at the Vet Visit

Cytopoint is only available through a licensed veterinarian. During your visit, your vet will assess your dog’s symptoms, rule out other causes of itching (like fleas or infections), and determine if Cytopoint is appropriate. The injection is quick — similar to a routine vaccine — and most dogs don’t even notice it.

Your vet may also recommend additional steps to manage environmental triggers or skin health, such as regular bathing, omega-3 supplements, or diet adjustments.

Are There Any Side Effects?

Cytopoint has been widely praised for its excellent safety profile. In clinical trials, the most common mild side effects included lethargy or digestive upset, but these were rare and short-lived. Because Cytopoint does not affect liver or kidney function, it’s considered a good option for older dogs or those already on other medications.

As with any injection, there’s a minimal risk of allergic reaction, but this is extremely uncommon. If your dog ever experiences unusual symptoms after treatment, contact your veterinarian immediately.

Is Cytopoint Right for Your Dog?

If your dog suffers from chronic itching, hot spots, or hair loss from scratching, Cytopoint could be life-changing. It’s especially beneficial for dogs whose allergies persist year-round or who can’t tolerate steroid treatments. Many pet owners notice not only reduced itching but also happier, more energetic pets after just one treatment cycle.

However, Cytopoint may not be a complete solution on its own. For some dogs, your veterinarian may combine it with other treatments, such as special shampoos, or allergen avoidance strategies, for a more comprehensive approach.

The Bottom Line

Cytopoint represents a major advance in veterinary dermatology. With its targeted mechanism, long-lasting relief, and minimal side effects, it offers a safe and effective option for dogs struggling with allergic itching. If constant scratching and discomfort are affecting your dog’s happiness — and your peace of mind — talk to your veterinarian about whether Cytopoint could help.

Have Questions about your Pet’s Allergies or Health? 

Schedule an appointment with your primary care veterinarian for a wellness check or visit our Burbank or Koreatown location if your pet has urgent symptoms. 

Call us at (818) 296-0700 in Burbank or (323) 302-5200 in Koreatown to speak with a member of our care team.